Three basic outbounds
proxy: through the proxy.direct: straight out, skipping the node.block: dropped, commonly for ad domains.
Use the built-in preset
v2rayN ships a "Bypass mainland (Whitelist)" policy: traffic matching mainland China domains and IPs goes direct, everything else through the proxy. For most people this is ideal — local sites aren't detoured, foreign ones are uniformly proxied. Switch it under Routing settings.
Add one custom rule
To force a local site direct: add a rule with domain domain:example.com, outbound direct, placed near the top (rules match top-down, first hit wins). Use geoip:cn for IP ranges, and point geosite:category-ads-all at block for ad filtering.